Samuel Leopold's first gallery appearance occurred at age 15 at the prestigious Gasperi Gallery in New Orleans. Just one year later, Leopold competed against numerous other student artists in southeast Louisiana to win a place in the United States Capitol Building through the 6th Annual Congressional Art Competition. His painting hung in the Capitol for two years. After ranking in several more North American competitions, Leopold was a finalist in the worldwide 10th Hyogo International Competition of Painting. His painting exhibited at Hyogo Prefectural Museum of Art, in Kobe, Japan.

Leopold has exhibited his work in hundreds of competitions and galleries across the country and around the world. Presently, more than 100 of his paintings are in collections in locations including Berlin, Geneva, Jerusalem, Paris, and Tokyo.

Leopold now lives in Chicago, where he has found a home for his artistic talents.