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Size Exclusion Chromatography

Size Exclusion Chromatography

This is a pretty straightforward drawing of the principles in size exclusion separations and chromatography. Little porous beads are packed together, and a solution of molecules passes through the packed bed of beads. The large molecules are too big for the pores of the beads and they quickly pass straight through the packed bed. Smaller molecules can explore more of the bead porosity and take a longer path – and longer time – through the bed. The underlying mechanism is different than, for example, paper chromatography, which you can try at home.

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Details

Size
5.0" x 7.0"
Medium
ink on paper

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